Article
[Comparative clinico-genetic studies of senile dementia and Alzheimer's disease].
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) - 1 Jan 1990
Siriachenko T M, Trubnikov V I, Voskresenskaia N I, Chentsova G M, Kalyn Ia B
Abstract excerpt
The families of 128 probands with senile dementia (SD) and Alzheimer's disease (AD) were entered into the study. The correlation between the familial and sporadic cases of the disease was established. A geneticomathematic analysis was employed to estimate the clinicogenealogical findings. Two genetic models (monogenous and multifactorial) were tested. The contribution of the genetic factors to SD and AD liability...
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