Article
Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.
European journal of endocrinology - 1 Nov 2007
Ma Jun, Nordman Sofia, Möllsten Anna, Falhammar Henrik, Brismar Kerstin, Dahlquist Gisela, Efendic Suad, Gu Harvest F
Abstract excerpt
OBJECTIVE: The distribution of Leu7Pro polymorphism in the neuropeptide Y gene shows a geographical north to south gradient of decreasing frequency, suggesting that it may be a population-specific causal variant. This polymorphism is found to be associated with diabetic nephropathy (DN) and coronary heart disease in Finnish women with type 1 diabetes (T1D). The present study aims to evaluate the susceptibility of...
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