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Article

Homophenotypic Aalpha R16H fibrinogen (Kingsport): uniquely altered polymerization associated with slower fibrinopeptide A than fibrinopeptide B release.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2007

Galanakis Dennis K, Neerman-Arbez Marguerite, Scheiner Tomas, Henschen Agnes, Hubbs Doris, Nagaswami Chandrasekaran, Weisel John W

Abstract excerpt

We detail for the first time the uniquely altered fibrin polymerization of homophenotypic Aalpha R16H dysfibrinogen. By polymerase chain reaction amplification and DNA sequencing, our new proposita's genotype consisted of a G>A transition encoding for Aalpha R16H, and an 11 kb Aalpha gene deletion. High-performance liquid chromatography disclosed fibrinopeptide A release approximately six times slower than its...

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PMID: 17982313
DOI: 10.1097/MBC.0b013e3282f10157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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