Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2007

Strutz-Seebohm Nathalie, Shojaiefard Manzar, Christie David, Tavare Jeremy, Seebohm Guiscard, Lang Florian

Abstract excerpt

The Na(+),Cl(-),creatine transporter CreaT (SLC6A8) mediates concentrative cellular uptake of creatine into a wide variety of cells. Previous observations disclosed that SLC6A8 transport activity is enhanced by mammalian target of rapamycin (mTOR) at least partially through the serum and glucocor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Consensus Sequence
Share to Creatine
Share to Immediate-Early Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Mimicry

Share to Mutant Proteins

Share to Oocytes

Share to Phosphatidylinositol 3-Kinases

Share to Xenopus

Source

Identifiers

PMID: 17982255
DOI: 10.1159/000110433

Genes

SGK1
SGK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17982255-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8.PMID 17982255Read ↗

PIKfyve-dependent regulation of the Cl- channel ClC-2.Semantic proximity Read ↗

Regulation of the Na(+)-coupled glutamate transporter EAAT3 by PIKfyve.Semantic proximity Read ↗

Regulation of the Na+,Cl- Coupled Creatine Transporter CreaT (SLC6A8) by the Janus Kinase JAK3.Semantic proximity Read ↗

Down-Regulation of the Na+,Cl- Coupled Creatine Transporter CreaT (SLC6A8) by Glycogen Synthase Kinase GSK3ß.Semantic proximity Read ↗

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.Semantic proximity Read ↗

Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth.Semantic proximity Read ↗

Molecular Mechanism of SLC6A8 Dysfunction with c.1699T > C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes.Semantic proximity Read ↗

Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3.Semantic proximity Read ↗

EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase.Semantic proximity Read ↗

Stimulation of the intestinal phosphate transporter SLC34A2 by the protein kinase mTOR.Semantic proximity Read ↗

The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter.Semantic proximity Read ↗

The serine/threonine kinases SGK1, 3 and PKB stimulate the amino acid transporter ASCT2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.