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Article

Genomic and proteomic profiles reveal the association of gelsolin to TP53 status and bladder cancer progression.

The American journal of pathology - 1 Nov 2007

Sanchez-Carbayo Marta, Socci Nicholas D, Richstone Lee, Corton Marta, Behrendt Nille, Wulkfuhle Julia, Bochner Bernard, Petricoin Emmanuel, Cordon-Cardo Carlos

Abstract excerpt

Bladder cancer transformation and immortalization require the inactivation of key regulatory genes, including TP53. Genotyping of a large cohort of bladder cancer patients (n = 256) using the TP53 GeneChip showed mutations in 103 cases (40.2%), the majority of them mapping to the DNA-binding core...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17982131
DOI: 10.2353/ajpath.2007.070338
PMCID: PMC2043525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17982131-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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