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Article

Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.

Molecular microbiology - 1 Jun 2006

Rickard Alexander H, Palmer Robert J, Blehert David S, Campagna Shawn R, Semmelhack Martin F, Egland Paul G, Bassler Bonnie L, Kolenbrander Paul E

Abstract excerpt

4,5-Dihydroxy-2,3-pentanedione (DPD), a product of the LuxS enzyme in the catabolism of S-ribosylhomocysteine, spontaneously cyclizes to form autoinducer 2 (AI-2). AI-2 is proposed to be a universal signal molecule mediating interspecies communication among bacteria. We show that mutualistic and abundant biofilm growth in flowing saliva of two human oral commensal bacteria, Actinomyces naeslundii T14V and...

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PMID: 16796680
DOI: 10.1111/j.1365-2958.2006.05202.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth.PMID 16796680Read ↗

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