Article
Characterization of the PduS cobalamin reductase of Salmonella enterica and its role in the Pdu microcompartment.
Journal of bacteriology - 1 Oct 2010
Cheng Shouqiang, Bobik Thomas A
Abstract excerpt
Salmonella enterica degrades 1,2-propanediol (1,2-PD) in a coenzyme B12 (adenosylcobalamin, AdoCbl)-dependent fashion. Salmonella obtains AdoCbl by assimilation of complex precursors, such as vitamin B12 and hydroxocobalamin. Assimilation of these compounds requires reduction of their central cobalt atom from Co3+ to Co2+ to Co+, followed by adenosylation to AdoCbl. In this work, the His6-tagged PduS cobalamin...
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