Article
Specific control of immunity by regulatory CD8 T cells.
Cellular & molecular immunology - 1 Feb 2005
Tang Xiao Lei, Smith Trevor Rf, Kumar Vipin
Abstract excerpt
T lymphocytes with dedicated suppressor function (Treg) play a crucial role in the homeostatic control of immunity in the periphery. Several Treg phenotypes have now been identified in the CD4 and CD8 T cell populations, suggesting their down-regulatory function in both human and animal models of autoimmunity, transplantation and tumor immunity. Here we will focus on the CD8 Treg population and their ability to...
Topics
- Animals
- Antigens
- CD8-Positive T-Lymphocytes
- Humans
- Immunity
- Phenotype
- Time Factors