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The role of phage display in therapeutic antibody discovery

18 Aug 2014

Abstract excerpt

Phage display involves the expression of selected proteins on the surface of filamentous phage through fusion with phage coat protein, with the genetic sequence packaged within, linking phenotype to genotype selection. When combined with antibody libraries, phage display allows for rapid in vitro selection of antigen-specific antibodies and recovery of their corresponding coding sequence. Large non-immune and...

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Share to Glycosylation and Glycoproteins Research
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PMID: 25135889
DOI: 10.1093/intimm/dxu082

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