Cationic transfectors increase accumulation in cultured tumor cells of radiolabeled antisense DNAs without entrapment.

Abstract excerpt

While cellular accumulations in culture of oligomers, such as interfering RNA and antisense DNA, are reported to benefit from the addition of transmembrane transfectors (TFs), the extent to which individual TFs improve cellular delivery is usually inferred and rarely measured. The goal of this investigation was to use radioactivity to measure in cells in culture the degree to which accumulations of DNA increased...

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