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Article

Enhancement of gene delivery to human airway epithelial cells in vitro using a peptide from the polyoma virus protein VP1.

The journal of gene medicine - 1 Jun 2005

Wiseman John W, Scott Emily S, Shaw Paul A, Colledge William H

Abstract excerpt

BACKGROUND: Current liposome-based gene delivery methods for therapeutic benefit are limited by their low efficiency. One possible way to improve gene expression is to include a peptide with a nuclear localization signal (NLS) to enhance the movement of the transfection complex from the cytoplasm to the nuclei of target cells. We have tested a synthetic peptide based on the amino terminal region of the polyoma...

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Identifiers

PMID: 15693032
DOI: 10.1002/jgm.721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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