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The risk of relapse in breast cancer patients is associated with MMP-9 gene polymorphism: a prospective study in a sample of the Iranian population.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2022

Kohan Leila, Mirhosseini Mahdis, Mortazavizadeh Seyed Mohammadreza

Abstract excerpt

We investigated the association of MMP-9 rs1056628 and rs17576 polymorphisms with breast cancer (BC) relapse in a cohort of prospectively observed BC patients. The polymorphisms were genotyped in 200 BC subjects with(case) and without(control) relapse by Tetra-primer Amplification Refractory Mutation System-Polymerase Chain Reaction (T-ARMS-PCR) method. A significant association was found between the rs1056628C...

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PMID: 35776084
DOI: 10.1080/15257770.2022.2094946

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