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Article

APC promoter methylation and protein expression in hepatocellular carcinoma.

Journal of cancer research and clinical oncology - 1 May 2008

Csepregi Antal, Röcken Christoph, Hoffmann Juliane, Gu Ping, Saliger Stephan, Müller Oliver, Schneider-Stock Regine, Kutzner Nadine, Roessner Albert, Malfertheiner Peter, Ebert Matthias P A

Abstract excerpt

PURPOSE: We investigated the impact of promoter methylation on APC protein expression in patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS: 50 patients [HCC (n=19), liver metastasis (n=19), cholangiocellular cancer (n=7), and benign liver tumors (n=5)] were studied for methylation using Methylight analysis. APC mutation was investigated by protein truncation test and direct sequencing of genomic...

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Share to Adenomatous Polyposis Coli Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

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Source

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Identifiers

PMID: 17973119
DOI: 10.1007/s00432-007-0321-y
PMCID: PMC2757596

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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