Article
Genetic association studies in digestive system malignancies.
Anticancer research - 1 Jan 2000
Tsigris Christos, Chatzitheofylaktou Agape, Xiromeritis Constantinos, Nikiteas Nikolaos, Yannopoulos Athanasios
Abstract excerpt
The multifactorial process of carcinogenesis in the digestive system involves mutations in oncogenes or tumor suppressor genes, as well as influence of environmental etiological factors. In recent years, common DNA polymorphisms in low penetrance genes emerged as genetic factors that seem to modulate an individual's susceptibility to malignancy, through interaction with environmental factors, such as diet or...
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