Article
Gastrointestinal Malignancy: Genetic Implications to Clinical Applications.
Cancer treatment and research - 1 Jan 2000
Lopez Nicole E, Yeh Jen Jen
Abstract excerpt
Alterations in the DNA sequences of genes, or mutations, have traditionally been viewed as the primary factors driving tumor progression, however, epigenetic evidence would suggest that some heritable traits are mediated by changes in DNA expression that are not dependent upon alterations in the primary DNA sequence. Advances in the genetic understanding of cancer have, in some instances, allowed for more precise...
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