Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythaematosus.

Annals of the rheumatic diseases - 1 Aug 2008

Mamtani M, Rovin B, Brey R, Camargo J F, Kulkarni H, Herrera M, Correa P, Holliday S, Anaya J-M, Ahuja S K

Abstract excerpt

OBJECTIVES: There is an enrichment of immune response genes that are subject to copy number variations (CNVs). However, there is limited understanding of their impact on susceptibility to human diseases. CC chemokine ligand 3 like-1 (CCL3L1) is a potent ligand for the HIV coreceptor, CC chemokine receptor 5 (CCR5), and we have demonstrated previously an association between CCL3L1-gene containing segmental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, Myelomonocytic
Share to CD3 Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CCL3

Share to Chemotaxis, Leukocyte

Share to Leukocytes

Share to Lupus Erythematosus, Systemic

Share to Lupus Nephritis

Share to Receptors, CCR5

Source

Open in PubMed Open full text

Identifiers

PMID: 17971457
DOI: 10.1136/ard.2007.078048
PMCID: PMC3786698

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythaematosus.PMID 17971457Read ↗

Copy number variants in genetic susceptibility and severity of systemic lupus erythematosus.Semantic proximity Read ↗

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.Semantic proximity Read ↗

Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.Semantic proximity Read ↗

Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European Americans.Semantic proximity Read ↗

CCR5 promoter region polymorphisms in systemic lupus erythematosus.Semantic proximity Read ↗

Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.Semantic proximity Read ↗

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.Semantic proximity Read ↗

HIV-1/AIDS susceptibility and copy number variation in CCL3L1, a gene encoding a natural ligand for HIV-1 co-receptor CCR5.Semantic proximity Read ↗

Across ancestries, HLA-B∗08:01∼DRB1∗03:01 (DR3) and HLA-DQA∗01:02 (DR2) increase the risk to develop juvenile-onset systemic lupus erythematosus through low complement C4 levelsSemantic proximity Read ↗

Effects of Complement <i>C4</i> Gene Copy Number Variations, Size Dichotomy, and <i>C4A</i> Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian PopulationsSemantic proximity Read ↗

Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.Semantic proximity Read ↗

Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.