Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.

Science (New York, N.Y.) - 4 Mar 2005

Gonzalez Enrique, Kulkarni Hemant, Bolivar Hector, Mangano Andrea, Sanchez Racquel, Catano Gabriel, Nibbs Robert J, Freedman Barry I, Quinones Marlon P, Bamshad Michael J, Murthy Krishna K, Rovin Brad H, Bradley William, Clark Robert A, Anderson Stephanie A, O'connell Robert J, Agan Brian K, Ahuja Seema S, Bologna Rosa, Sen Luisa, Dolan Matthew J, Ahuja Sunil K

Abstract excerpt

Segmental duplications in the human genome are selectively enriched for genes involved in immunity, although the phenotypic consequences for host defense are unknown. We show that there are significant interindividual and interpopulation differences in the copy number of a segmental duplication encompassing the gene encoding CCL3L1 (MIP-1alphaP), a potent human immunodeficiency virus-1 (HIV-1)-suppressive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokines, CC
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Gene Duplication

Share to Pan troglodytes

Share to Public Health

Share to Racial Groups

Share to Receptors, CCR5

Source

Identifiers

PMID: 15637236
DOI: 10.1126/science.1101160

Genes

CCR5
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.PMID 15637236Read ↗

HIV-1/AIDS susceptibility and copy number variation in CCL3L1, a gene encoding a natural ligand for HIV-1 co-receptor CCR5.Semantic proximity Read ↗

Susceptibility to HIV/AIDS: an individual characteristic we can measure?Semantic proximity Read ↗

CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythaematosus.Semantic proximity Read ↗

Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children.Semantic proximity Read ↗

Gene copy number regulates the production of the human chemokine CCL3-L1Semantic proximity Read ↗

CCL3L1 dose and HIV-1 susceptibility.Semantic proximity Read ↗

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.Semantic proximity Read ↗

Host CCL3L1 Gene Copy Number in Relation to HIV-1-Specific CD4+ and CD8+ T-Cell Responses and Viral Load in South African WomenSemantic proximity Read ↗

CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection.Semantic proximity Read ↗

Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys.Semantic proximity Read ↗

CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans.Semantic proximity Read ↗

CCL3L1 copy number variation and susceptibility to HIV-1 infection: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.