Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1/AIDS susceptibility and copy number variation in CCL3L1, a gene encoding a natural ligand for HIV-1 co-receptor CCR5.

Cytogenetic and genome research - 1 Jan 2008

Nakajima T, Kaur G, Mehra N, Kimura A

Abstract excerpt

Variations of gene copy number in the human genome are increasingly recognized as a genetic factor in phenotypic variation. Human CC chemokine ligand 3-like 1 gene (CCL3L1), which is located on human chromosome 17q11.2, is highly variable in copy number owing to having a hot spot for segmental duplications. CCL3L1, a natural ligand for HIV-1 co-receptor CCR5, is a potent HIV-1-suppressive chemokine. CCL3L1 copy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Chemokine CCL3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CCR5 gene

Share to Gene Dosage

Share to Genetic Predisposition to Disease

Share to Receptors, CCR5

Source

Identifiers

PMID: 19287150
DOI: 10.1159/000184703

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1/AIDS susceptibility and copy number variation in CCL3L1, a gene encoding a natural ligand for HIV-1 co-receptor CCR5.PMID 19287150Read ↗

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.Semantic proximity Read ↗

Gene copy number regulates the production of the human chemokine CCL3-L1Semantic proximity Read ↗

CCL3L1 copy number variation and susceptibility to HIV-1 infection: a meta-analysis.Semantic proximity Read ↗

Population-specific profiling of CCL3L1 copy number of the three major ethnic groups in Malaysia and the implication on HIV susceptibility.Semantic proximity Read ↗

The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.Semantic proximity Read ↗

Lower copy numbers of the chemokine CCL3L1 gene in patients with chronic hepatitis C.Semantic proximity Read ↗

CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection.Semantic proximity Read ↗

CCL3L1 dose and HIV-1 susceptibility.Semantic proximity Read ↗

Identification of new variants within the two functional genes CCL3 and CCL3L encoding the CCL3 (MIP-1alpha) chemokine: implications for HIV-1 infection.Semantic proximity Read ↗

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung functionSemantic proximity Read ↗

Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children.Semantic proximity Read ↗

Population structure in copy number variation and SNPs in the CCL4L chemokine gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.