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Article

Copy number variants in genetic susceptibility and severity of systemic lupus erythematosus.

Cytogenetic and genome research - 1 Jan 2008

Ptacek T, Li X, Kelley J M, Edberg J C

Abstract excerpt

Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterized by the presence of auto-antibodies to nuclear antigens, immune complex deposition, and subsequent tissue destruction. Early studies in twins suggested that SLE has, at least in part, a genetic basis, and a role for class II alleles in the major histocompatibility complex has been known for over 30 years. Through both linkage...

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Identifiers

PMID: 19287148
DOI: 10.1159/000184701
PMCID: PMC2826785

Genes

TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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