Association of interleukin-10 gene promoter polymorphisms with chronic and aggressive periodontitis.

doi:10.1111/j.1601-0825.2011.01872.x

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Article

Association of interleukin-10 gene promoter polymorphisms with chronic and aggressive periodontitis.

Oral diseases - 1 Apr 2012

Jaradat S M, Ababneh K T, Jaradat S A, Abbadi M S, Taha A H, Karasneh J A, Haddad H I

Abstract excerpt

OBJECTIVE: Interleukin-10 gene promoter polymorphisms have been associated with interleukin-10 decreased production, thereby playing a role in the pathogenesis of periodontitis. This study aimed to investigate whether interleukin-10 single nucleotide polymorphisms at positions -1087(G/A) and -597(C/A) are associated with generalised chronic periodontitis and localised aggressive periodontitis. METHODS: Genomic...

Topics

Adenine
Adolescent
Adult
Aggressive Periodontitis
Alleles
Chronic Periodontitis
Cytosine
Female
Gene Frequency
Genetic Markers
Genotype
Guanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-10

Male

Middle Aged

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 22077544
DOI: 10.1111/j.1601-0825.2011.01872.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22077544-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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