Article
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis.
Journal of periodontology - 1 Mar 2007
Sumer A Pinar, Kara Nurten, Keles Gonca Cayir, Gunes Sezgin, Koprulu Hulya, Bagci Hasan
Abstract excerpt
BACKGROUND: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms in the IL-10 gene might be useful as a marker to diagnose susceptibility to periodontitis. Therefore, the aim of this study was to investigate the association between IL-10 gene...
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