Article
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis.
Journal of periodontology - 1 Mar 2007
Sumer A Pinar, Kara Nurten, Keles Gonca Cayir, Gunes Sezgin, Koprulu Hulya, Bagci Hasan
Abstract excerpt
BACKGROUND: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms in the IL-10 gene might be useful as a marker to diagnose susceptibilit...
Topics
- Adult
- Aged
- Alleles
- Case-Control Studies
- Chi-Square Distribution
- Chronic Disease
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-10
- Male
- Middle Aged
- Odds Ratio
- Periodontitis
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide