Article
Host Transmission of <i>Salmonella enterica</i> Serovar Typhimurium Is Controlled by Virulence Factors and Indigenous Intestinal Microbiota
29 Oct 2007
Abstract excerpt
Transmission is an essential stage of a pathogen's life cycle and remains poorly understood. We describe here a model in which persistently infected 129X1/SvJ mice provide a natural model of Salmonella enterica serovar Typhimurium transmission. In this model only a subset of the infected mice, termed supershedders, shed high levels (>10(8) CFU/g) of Salmonella serovar Typhimurium in their feces and, as a result,...
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