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LAPTM4B gene polymorphism and endometrial carcinoma risk and prognosis.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2013

Meng Fanling, Li Huiyan, Zhou Rouli, Luo Chang, Hu Yuanlong, Lou Ge

Abstract excerpt

A novel gene called LAPTM4B (lysosome-associated protein transmembrane 4 beta) plays several crucial roles in carcinogenesis. In this case-control study, we investigated the relationship between LAPTM4B gene polymorphism and susceptibility to endometrial carcinoma (EC). In an adjusted multivariate logistic regression analyses, subjects with the LAPTM4B*1/2 and *2/2 genotypes respectively exhibited 1.572-fold (95%...

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Identifiers

PMID: 23312008
DOI: 10.3109/1354750X.2012.752526

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