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Article

Paternal care paradoxically increases offspring seizure susceptibility in the El mouse model of epilepsy.

Epilepsy & behavior : E&B - 1 Feb 2008

Orefice Lauren L, Heinrichs Stephen C

Abstract excerpt

The El mouse is a model of idiopathic epilepsy in which seizures emerge on Postnatal Days (PNDs) 80-90, although time to first seizure can be modified by experiential factors including handling during development and history of past seizures. This study tested the hypothesis that a significant increase in the amount of parental investment would impact seizure susceptibility in adult El offspring. The study used a...

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Source

Identifiers

PMID: 17964859
DOI: 10.1016/j.yebeh.2007.09.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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