Article
Quality of rearing guides expression of behavioral and neural seizure phenotypes in EL mice.
Brain research - 13 Mar 2009
Leussis Melanie P, Heinrichs Stephen C
Abstract excerpt
The present studies employed behavioral and neural markers of seizure-related plasticity to examine the relative contributions of genetic predisposition versus rearing environment in generating adult phenotypes in EL mice, a stress-induced animal model of epilepsy. Early environment was manipulated by cross-fostering pups of the EL strain to a seizure-resistant CD-1 control strain of mouse. The impact of changes...
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