Article
Failure to recognize multiple endocrine neoplasia 2B: more common than we think?
Annals of surgical oncology - 1 Jan 2008
Wray Curtis J, Rich Thereasa A, Waguespack Steven G, Lee Jeffrey E, Perrier Nancy D, Evans Douglas B
Abstract excerpt
BACKGROUND: Multiple endocrine neoplasia 2B (MEN2B) has a classic childhood phenotypic presentation characterized by mucosal neuromas and marfanoid habitus. However, the diagnosis of MEN2B is often delayed beyond childhood, at which time medullary thyroid carcinoma (MTC) may be regionally advanced or metastatic. We examined the extent of this delay and its impact on the treatment of MTC. METHODS: Patients in the...
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