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Article

Multiple endocrine neoplasia type 2: an overview.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2011

Moline Jessica, Eng Charis

Abstract excerpt

Multiple endocrine neoplasia type 2 is historically composed of three clinical subtypes, all of which are associated with germline mutations in the RET proto-oncogene. Multiple endocrine neoplasia type 2A, familial medullary thyroid carcinoma, and multiple endocrine neoplasia type 2B are collectively associated with a 70-100% risk of medullary thyroid carcinoma by age 70 years. Pheochromocytomas are identified in...

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Identifiers

PMID: 21552134
DOI: 10.1097/GIM.0b013e318216cc6d

Genes

RET

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