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Article

The T1799A<i>BRAF</i>Mutation Is Present in Iris Melanoma

25 Oct 2007

Abstract excerpt

PURPOSE: An activating mutation in exon 15 of the BRAF gene has been found in a high proportion of cutaneous pigmented lesions, but only in one case of uveal melanoma. Iris melanoma is the least common uveal melanoma and displays a less aggressive clinical course compared with posterior uveal melanoma. To date, no study has been conducted to investigate the T1799A mutation in iris melanoma. The purpose of this...

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PMID: 17962436
DOI: 10.1167/iovs.07-0440

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