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Article

Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease.

Genes and immunity - 1 Jan 2008

Callaghan M J, Rockett K, Banner C, Haralambous E, Betts H, Faust S, Maiden M C J, Kroll J S, Levin M, Kwiatkowski D P, Pollard A J

Abstract excerpt

Adhesion between the opacity-associated adhesin (Opa) proteins of Neisseria meningitidis and human carcino-embryonic antigen cell adhesion molecule (CEACAM) proteins is an important stage in the pathogenesis of meningococcal disease, a globally important bacterial infection. Most disease is caused by a small number of meningococcal genotypes known as hyperinvasive lineages. As these are also carried...

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Topics

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Share to Adhesins, Bacterial
Share to Antigens, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoembryonic Antigen

Share to Data Interpretation, Statistical

Share to Homozygote

Share to Linkage Disequilibrium

Share to Meningococcal Infections

Share to Neisseria meningitidis

Source

Open in PubMed Open full text

Identifiers

PMID: 17960155
DOI: 10.1038/sj.gene.6364442
PMCID: PMC7094765

Genes

CEACAM1
CEACAM6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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