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Article

Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors.

Molecular microbiology - 1 Nov 2003

de Jonge Marien I, Hamstra Hendrik Jan, van Alphen Loek, Dankert Jacob, van der Ley Peter

Abstract excerpt

The opacity (Opa) proteins of pathogenic Neisseria spp. are adhesins, which play an important role in adhesion and invasion of host cells. Most members of this highly variable family of outer membrane proteins can bind to the human carcinoembryonic antigen-related cell adhesion molecules (CEACAMs). Several studies have identified the Opa-binding region on the CEACAM receptors; however, not much is known about the...

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Source

Identifiers

PMID: 14617157
DOI: 10.1046/j.1365-2958.2003.03749.x

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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