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Article

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.

Leukemia research - 1 Jun 2011

Majid Aneela, Lin Thet Thet, Best Giles, Fishlock Keith, Hewamana Saman, Pratt Guy, Yallop Deborah, Buggins Andrea G S, Wagner Simon, Kennedy Ben J, Miall Fiona, Hills Robert, Devereux Stephen, Oscier David G, Dyer Martin J S, Fegan Chris, Pepper Chris

Abstract excerpt

The world of chronic lymphocytic leukemia (CLL) research is awash with prognostic markers. However, very few of the current group play a clearly defined role in the pathology of this disease and even fewer represent a tractable therapeutic target. One such marker that fulfils both of these criteria is the integrin CD49d. This molecule been implicated in the capacity of CLL cells to migrate into lymphoid tissues...

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Share to ADP-ribosyl Cyclase 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Receptors, CXCR4

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Source

Identifiers

PMID: 21093051
DOI: 10.1016/j.leukres.2010.10.022

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL.PMID 21093051Read ↗

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