Article
Effect of adherence to HAART on virologic outcome and on the selection of resistance-conferring mutations in NNRTI- or PI-treated patients.
HIV clinical trials - 1 Jan 2000
Maggiolo Franco, Airoldi Monica, Kleinloog Hendrik Daniël, Callegaro Annapaola, Ravasio Veronica, Arici Claudio, Bombana Enrico, Suter Fredy
Abstract excerpt
BACKGROUND: The effect of adherence on the risk of virologic failure and mutations selection was verified in a prospective study. METHOD: At baseline, all patients had a viral load (VL) <50 copies/mL and completed a self-reported questionnaire. Patients were followed for the subsequent 4 months to document virologic rebound (VL > 50 copies/mL). RESULTS: 1,133 patients completed 2,240 questionnaires/follow-up...
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