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Article

No genetic bottleneck in Plasmodium falciparum wild-type Pfcrt alleles reemerging in Hainan Island, China, following high-level chloroquine resistance.

Antimicrobial agents and chemotherapy - 1 Jan 2008

Chen Nanhua, Gao Qi, Wang Shanqing, Wang Guangze, Gatton Michelle, Cheng Qin

Abstract excerpt

Chloroquine-resistant Plasmodium falciparum was highly prevalent in Hainan, China, in the 1970s. Twenty-five years after cessation of chloroquine therapy, the prevalence of P. falciparum wild-type Pfcrt alleles has risen to 36% (95% confidence interval, 22.1 to 52.4%). The diverse origins of wild...

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Identifiers

PMID: 17954685
DOI: 10.1128/AAC.00711-07
PMCID: PMC2223894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17954685-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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