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Article

The Sri Lankan paradox: high genetic diversity in Plasmodium vivax populations despite decreasing levels of malaria transmission.

Parasitology - 1 Jun 2014

Gunawardena Sharmini, Ferreira Marcelo U, Kapilananda G M G, Wirth Dyann F, Karunaweera Nadira D

Abstract excerpt

Here we examined whether the recent dramatic decline in malaria transmission in Sri Lanka led to a major bottleneck in the local Plasmodium vivax population, with a substantial decrease in the effective population size. To this end, we typed 14 highly polymorphic microsatellite markers in 185 P. vivax patient isolates collected from 13 districts in Sri Lanka over a period of 5 years (2003-2007). Overall, we found...

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Share to Linkage Disequilibrium
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24533989
DOI: 10.1017/S0031182013002278
PMCID: PMC7485621

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