Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of the PTEN gene in a human hepatic angiosarcoma.

Cancer genetics and cytogenetics - 15 Oct 2007

Tate Genshu, Suzuki Takao, Mitsuya Toshiyuki

Abstract excerpt

The phosphatase and tensin homolog (mutated in multiple advanced cancers 1) gene, or PTEN, encodes a lipid phosphatase that contains a PTPase domain and a C2 domain and plays a role as a tumor suppressor that negatively regulates the cell-survival signaling pathway initiated by phosphatidylinosit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Breast Neoplasms
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemangiosarcoma

Share to Immunohistochemistry

Share to Liver Neoplasms

Share to Polymerase Chain Reaction

Share to PTEN Phosphohydrolase

Source

Identifiers

PMID: 17954274
DOI: 10.1016/j.cancergencyto.2007.07.017

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17954274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation of the PTEN gene in a human hepatic angiosarcoma.PMID 17954274Read ↗

Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.Semantic proximity Read ↗

Actionable mutations in canine hemangiosarcoma.Semantic proximity Read ↗

Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma.Semantic proximity Read ↗

Molecular Profile of Canine Hemangiosarcoma and Potential Novel Therapeutic TargetsSemantic proximity Read ↗

Molecular Profile of Canine Hemangiosarcoma and Potential Novel Therapeutic TargetsSemantic proximity Read ↗

Molecular subtypes in canine hemangiosarcoma reveal similarities with human angiosarcoma.Semantic proximity Read ↗

Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics.Semantic proximity Read ↗

A novel mutation of the PTEN gene in a Japanese patient with Cowden syndrome and bilateral breast cancer.Semantic proximity Read ↗

Angiogenesis-related gene mutations drive a subset of angiosarcomas.Semantic proximity Read ↗

Somatic RHOA mutation in angioimmunoblastic T cell lymphomaSemantic proximity Read ↗

Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish.Semantic proximity Read ↗

Mutations of p53 tumor-suppressor gene in angiosarcoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.