Article
Genotyping of GII.4 and GIIb norovirus RT-PCR amplicons by RFLP analysis.
Journal of virological methods - 1 Feb 2008
Ramirez Stefania, Giammanco Giovanni M, De Grazia Simona, Colomba Claudia, Martella Vito, Arista Serenella
Abstract excerpt
GII.4 and GIIb/Hilversum norovirus (NoV) strains appear to have a prominent epidemiological role in outbreaks or sporadic cases of human gastroenteritis. Sequence analysis, although laborious, is the reference method used for characterization of noroviruses. In this study a screening test is proposed to characterize GIIb and GII.4 NoVs based on restriction fragment length polymorphism (RFLP) analysis of amplicons...
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