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Article

Genomic analysis of the evolutionary lineage of Norovirus GII.4 from archival specimens during 1975-1987 in Tokyo.

Journal of medical virology - 1 Feb 2017

Mori Kohji, Chu Pei-Yu, Motomura Kazushi, Somura Yoshiko, Nagano Miyuki, Kimoto Kana, Akiba Tetsuya, Kai Akemi, Sadamasu Kenji

Abstract excerpt

This study aimed to analyze NoV GII.4 sequences from archival specimens obtained during 1975-1987 by comparing them with reference sequences. The first NoV GII.P4_GII.4 sequence was identified in 1980. NoV GII.4 collected in 1970 had a GII.P1_GII.4 sequence. These results indicate that the GII.P4_GII.4 sequence may be the result of a recombination that might have occurred around 1980. Amino acid substitutions...

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PMID: 27380721
DOI: 10.1002/jmv.24624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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