Article
Identification of differentially expressed genes in microsatellite stable HNPCC and sporadic colon cancer.
The Journal of surgical research - 1 Jan 2008
Lee Won-Suk, Seo Gilju, Shin Hee Jung, Yun Seong Hyeon, Yun Haeran, Choi Naeyun, Lee Jinseon, Son Daesoon, Cho Jisook, Kim Jhingook, Cho Yong Beom, Chun Ho-Kyung, Lee Woo Yong
Abstract excerpt
BACKGROUND: Some sporadic colon cancers and hereditary nonpolyposis colorectal cancer (HNPCC) have been known by a constitutional defect in mismatch gene repair (MMR) and dysfunction in of this MMR system, which lead to an aberrant phenotype that can cause microsatellite instability. However, the clinicopathologic features of still existing microsatellite stable (MSS) colon cancer remain to be investigated....
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