Article
IL-6-174 C/G polymorphism in the gastroenteropancreatic neuroendocrine tumors (GEP-NETs).
Experimental and molecular pathology - 1 Dec 2007
Berković Maja Cigrovski, Jokić Mladen, Marout Jasminka, Radosević Senka, Zjacić-Rotkvić Vanja, Kapitanović Sanja
Abstract excerpt
IL-6 is a pleiotropic cytokine with still controversial role in tumorigenesis of different cancer types. Its promoter SNP-174 C/G is associated with increased IL-6 transcription and in some tumor types with elevated IL-6 serum levels. The role of IL-6 polymorphisms and IL-6 serum values and their correlation in the gastroenteropancreatic neuroendocrine tumors is lacking. We investigated for the first time...
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