Article
Interleukin-6 -174 G/C promoter gene polymorphism in nasal polyposis and asthma.
Rhinology - 1 Mar 2013
Kosugi E M, de Camargo-Kosugi C M, Hirai E R, Mendes-Neto J A, Gregorio L C, Guerreiro-da-Silva I D C, Weckx L L M
Abstract excerpt
BACKGROUND: Interleukin-6 (IL-6) is an inflammatory mediator linked to nasal polyposis and asthma, with a single nucleotide poly- morphism -174 G/C that seems to promote an inflammatory status. We aimed to analyze the relationship between this poly-morhism and asthmatic nasal polyposis patients. METHODOLOGY: Cross-sectional study to investigate IL-6 - 174 G/C genotypes of 45 nasal polyposis with asthma patients,...
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