Article
Susceptible alleles of the CD40 and CTLA-4 genes are not associated with the relapse after antithyroid withdrawal in Graves' disease.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2007
Kim Kyung Won, Park Young Joo, Kim Tae Yong, Park Do Joon, Park Kyong Soo, Cho Bo Youn
Abstract excerpt
In this study, we investigated whether the CD40 or cytotoxic T lymphocyte-associated molecules-4 (CTLA-4) polymorphisms, which are associated with the susceptibility of Graves' disease (GD), can predict the clinical outcome after antithyroid drug (ATD) withdrawal. All patients with GD were treated with ATD. GD patients were divided into two groups: remission or failure. The remission group was defined as patients...
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