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Article

Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008

Domschke Katharina, Hohoff Christa, Jacob Christian, Maier Wolfgang, Fritze Jürgen, Bandelow Borwin, Krakowitzky Petra, Kästner Florian, Rothermundt Matthias, Arolt Volker, Deckert Jürgen

Abstract excerpt

There is strong evidence for a genetic contribution to the pathogenesis of panic disorder, with a recent linkage study pointing toward a risk locus on chromosome 4q31-q34 [Kaabi et al., 2006]. Since the neuropeptide Y (NPY) system has been reported to be involved in the pathophysiology of anxiety and in particular panic disorder and the genes coding for NPY Y1, Y2, and Y5 receptors are located in the suggested...

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PMID: 17948870
DOI: 10.1002/ajmg.b.30629

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NPY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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