Article
Nerve growth factor promotes TLR4 signaling-induced maturation of human dendritic cells in vitro through inducible p75NTR 1.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2007
Jiang Yingming, Chen Guoyou, Zhang Yi, Lu Lin, Liu Shuxun, Cao Xuetao
Abstract excerpt
Nerve growth factor (NGF) has been shown to play important roles in the differentiation, function, and survival of immune cells, contributing to immune responses and pathogenesis of autoimmune diseases. Dendritic cells (DCs) are a potent initiator for immune and inflammatory responses upon recognition of pathogens via Toll-like receptors (TLR). However, expression of NGF and its receptors on human...
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