Article
No evidence of association of the MYO9B polymorphisms with celiac disease in the Spanish population.
Tissue antigens - 1 Dec 2006
Núñez C, Márquez A, Varadé J, Martínez A, Polanco I, Maluenda C, Fernández-Arquero M, de la Concha E G, Urcelay E
Abstract excerpt
Inconsistent results concerning the association of polymorphisms in the MYO9B gene with celiac disease (CD) have been recently published. This gene encodes a myosin with a guanosine-triphosphatase (GTPase)-activating protein domain for the Rho-family of small G proteins, which are involved in cytoskeleton remodeling and therefore potentially involved in intestinal permeability. Functional and positional reasons...
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