Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch 1 promotes cisplatin-resistant gastric cancer formation by upregulating lncRNA AK022798 expression

12 Mar 2015

Abstract excerpt

Gastric cancer is now the fourth most common malignancy and the second leading cause of death because of cancer. The resistance to anticancer drugs is the main cause of chemotherapy failure. In this study, we explored the role of Notch 1 and long noncoding RNA (lncRNA) in drug-resistant gastric cancer formation. First, we found that Notch 1 was highly expressed in the cisplatin-resistant gastric cancer cell lines...

Topics

Join the communities discussing this publication.

Cancer-related molecular mechanisms research
MicroRNA in disease regulation
Mycobacterium research and diagnosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25763542
DOI: 10.1097/cad.0000000000000227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch 1 promotes cisplatin-resistant gastric cancer formation by upregulating lncRNA AK022798 expressionPMID 25763542Read ↗

Portrayal of the complex molecular landscape of multidrug resistance in gastric cancer: Unveiling the potential targetsSemantic proximity Read ↗

LncRNA DANCR accelerates the development of multidrug resistance of gastric cancer.Semantic proximity Read ↗

Long Non-Coding RNA in Gastric Cancer: Mechanisms and Clinical Implications for Drug ResistanceSemantic proximity Read ↗

Multidrug resistance in gastric cancer: recent research advances and ongoing therapeutic challengesSemantic proximity Read ↗

LncRNA SNHG5 promotes cisplatin resistance in gastric cancer via inhibiting cell apoptosis.Semantic proximity Read ↗

Functional Role of the SLC7A11-AS1/xCT Axis in the Development of Gastric Cancer Cisplatin-resistance by a GSH-dependent MechanismSemantic proximity Read ↗

Silencing of long non-coding RNA ANRIL inhibits the development of multidrug resistance in gastric cancer cellsSemantic proximity Read ↗

miR‑1 reverses multidrug resistance in gastric cancer cells via downregulation of sorcin through promoting the accumulation of intracellular drugs and apoptosis of cellsSemantic proximity Read ↗

The role of microRNA in cisplatin resistance or sensitivitySemantic proximity Read ↗

Long Noncoding RNAs as Biotargets in Cisplatin-Based Drug ResistanceSemantic proximity Read ↗

miR-181a suppresses autophagy and sensitizes gastric cancer cells to cisplatinSemantic proximity Read ↗

Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.