Article
The relationship between evolutionary and physiological variation in hemoglobin.
Proceedings of the National Academy of Sciences of the United States of America - 23 Oct 2007
Milo Ron, Hou Jennifer H, Springer Michael, Brenner Michael P, Kirschner Marc W
Abstract excerpt
Physiological and evolutionary adaptations operate at very different time scales. Nevertheless, there are reasons to believe there should be a strong relationship between the two, as together they modify the phenotype. Physiological adaptations change phenotype by altering certain microscopic parameters; evolutionary adaptation can either alter genetically these same parameters or others to achieve distinct or...
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