Article
Conservation and diversity of ancient hemoglobins in Bacteria.
Biochemical and biophysical research communications - 12 May 2006
Miranda Jj L
Abstract excerpt
A group of single-domain proteins in Bacteria similar to thermoglobin, an oxygen-avid hemoglobin representative of the ancestral form, reveals the primordial structure, function, and evolvability of the family. Conserved residues at specific positions function to bind ligand or participate in hydrophobic packing of the protein core during protein folding. A potential hydrogen bond network consisting of a tyrosine...
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