Article
Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation.
Journal of virology - 1 Dec 2007
Dölken Lars, Perot Jonathan, Cognat Valérie, Alioua Abdelmalek, John Matthias, Soutschek Jürgen, Ruzsics Zsolt, Koszinowski Ulrich, Voinnet Olivier, Pfeffer Sébastien
Abstract excerpt
MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate gene expression at the posttranscriptional level. Originally identified in a variety of organisms ranging from plants to mammals, miRNAs have recently been identified in several viruses. Viral miRNAs may play a role in modulating both viral and host gene expression. Here, we report on the identification and characterization of 18 viral miRNAs...
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