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MicroRNAs expressed by human cytomegalovirus

12 Mar 2020

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs about 22 nucleotides in length, which play an important role in gene regulation of both eukaryotes and viruses. They can promote RNA cleavage and repress translation via base-pairing with complementary sequences within mRNA molecules. MAIN BODY: Human cytomegalovirus (HCMV) encodes a large number of miRNAs that regulate transcriptions of both host cells and...

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PMID: 32164742
DOI: 10.1186/s12985-020-1296-4

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