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Article

WISP3 suppresses insulin-like growth factor signaling in human chondrocytes.

Molecular and cellular endocrinology - 15 Dec 2007

Cui Rong-Rong, Huang Jiao, Yi Lu, Xie Hui, Zhou Hou-De, Yuan Ling-Qing, Wang Min, Peng Yi-Qun, Luo Xiang-Hang, Liao Er-Yuan

Abstract excerpt

WISP3 is essential for maintaining cartilage integrity mainly by regulating the expression of collagen II, and mutations of WISP3 linked to spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA) can compromise this function and lead to cartilage loss. The aim of this study was to evaluate the effect of WISP3 on insulin-like growth factor (IGF) signaling in human chondrocytes, investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17942216
DOI: 10.1016/j.mce.2007.08.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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